The INBIOSA project brings together a group of experts across many disciplines who believe that science requires a revolutionary transformative step in order to address many of the vexing challenges presented by the world. It is INBIOSA’s purpose to enable the focused collaboration of an interdisciplinary community of original thinkers. This paper sets out the case for support for this effort. The focus of the transformative research program proposal is biology-centric. We admit that biology to date has been more fact-oriented (...) and less theoretical than physics. However, the key leverageable idea is that careful extension of the science of living systems can be more effectively applied to some of our most vexing modern problems than the prevailing scheme, derived from abstractions in physics. While these have some universal application and demonstrate computational advantages, they are not theoretically mandated for the living. A new set of mathematical abstractions derived from biology can now be similarly extended. This is made possible by leveraging new formal tools to understand abstraction and enable computability. [The latter has a much expanded meaning in our context from the one known and used in computer science and biology today, that is "by rote algorithmic means", since it is not known if a living system is computable in this sense (Mossio et al., 2009).] Two major challenges constitute the effort. The first challenge is to design an original general system of abstractions within the biological domain. The initial issue is descriptive leading to the explanatory. There has not yet been a serious formal examination of the abstractions of the biological domain. What is used today is an amalgam; much is inherited from physics (via the bridging abstractions of chemistry) and there are many new abstractions from advances in mathematics (incentivized by the need for more capable computational analyses). Interspersed are abstractions, concepts and underlying assumptions “native” to biology and distinct from the mechanical language of physics and computation as we know them. A pressing agenda should be to single out the most concrete and at the same time the most fundamental process-units in biology and to recruit them into the descriptive domain. Therefore, the first challenge is to build a coherent formal system of abstractions and operations that is truly native to living systems. Nothing will be thrown away, but many common methods will be philosophically recast, just as in physics relativity subsumed and reinterpreted Newtonian mechanics. -/- This step is required because we need a comprehensible, formal system to apply in many domains. Emphasis should be placed on the distinction between multi-perspective analysis and synthesis and on what could be the basic terms or tools needed. The second challenge is relatively simple: the actual application of this set of biology-centric ways and means to cross-disciplinary problems. In its early stages, this will seem to be a “new science”. This White Paper sets out the case of continuing support of Information and Communication Technology (ICT) for transformative research in biology and information processing centered on paradigm changes in the epistemological, ontological, mathematical and computational bases of the science of living systems. Today, curiously, living systems cannot be said to be anything more than dissipative structures organized internally by genetic information. There is not anything substantially different from abiotic systems other than the empirical nature of their robustness. We believe that there are other new and unique properties and patterns comprehensible at this bio-logical level. The report lays out a fundamental set of approaches to articulate these properties and patterns, and is composed as follows. -/- Sections 1 through 4 (preamble, introduction, motivation and major biomathematical problems) are incipient. Section 5 describes the issues affecting Integral Biomathics and Section 6 -- the aspects of the Grand Challenge we face with this project. Section 7 contemplates the effort to formalize a General Theory of Living Systems (GTLS) from what we have today. The goal is to have a formal system, equivalent to that which exists in the physics community. Here we define how to perceive the role of time in biology. Section 8 describes the initial efforts to apply this general theory of living systems in many domains, with special emphasis on crossdisciplinary problems and multiple domains spanning both “hard” and “soft” sciences. The expected result is a coherent collection of integrated mathematical techniques. Section 9 discusses the first two test cases, project proposals, of our approach. They are designed to demonstrate the ability of our approach to address “wicked problems” which span across physics, chemistry, biology, societies and societal dynamics. The solutions require integrated measurable results at multiple levels known as “grand challenges” to existing methods. Finally, Section 10 adheres to an appeal for action, advocating the necessity for further long-term support of the INBIOSA program. -/- The report is concluded with preliminary non-exclusive list of challenging research themes to address, as well as required administrative actions. The efforts described in the ten sections of this White Paper will proceed concurrently. Collectively, they describe a program that can be managed and measured as it progresses. (shrink)

It is a widespread intuition that the coherence of independent reports provides a powerful reason to believe that the reports are true. Formal results by Huemer, M. 1997. “Probability and Coherence Justification.” Southern Journal of Philosophy 35: 463–72, Olsson, E. 2002. “What is the Problem of Coherence and Truth?” Journal of Philosophy XCIX : 246–72, Olsson, E. 2005. Against Coherence: Truth, Probability, and Justification. Oxford University Press., Bovens, L., and S. Hartmann. 2003. Bayesian Epistemology. Oxford University Press, prove that, under (...) certain conditions, coherence cannot increase the probability of the target claim. These formal results, known as ‘the impossibility theorems’ have been widely discussed in the literature. They are taken to have significant epistemic upshot. In particular, they are taken to show that reports must first individually confirm the target claim before the coherence of multiple reports offers any positive confirmation. In this paper, I dispute this epistemic interpretation. The impossibility theorems are consistent with the idea that the coherence of independent reports provides a powerful reason to believe that the reports are true even if the reports do not individually confirm prior to coherence. Once we see that the formal discoveries do not have this implication, we can recover a model of coherence justification consistent with Bayesianism and these results. This paper, thus, seeks to turn the tide of the negative findings for coherence reasoning by defending coherence as a unique source of confirmation. (shrink)

Afin d’échapper au dilemme de la fondation, Karen Bennett a proposé une thèse selon laquelle la relation de fondation serait superinterne, c’est-à-dire qu’elle reposerait entièrement sur la nature du relatum de gauche. Si cette approche peut de prime abord sembler particulièrement convaincante en raison de sa simplicité et de son élégance, un examen plus minutieux révèle toutefois d’importantes difficultés. Dans cet article, j’élabore de nombreuses critiques contre la thèse de la superinternalité qui s’avère moins intuitive qu’elle ne le laisse paraître. (...) Je considère ensuite l’alternative que représente la sémantique métaphysique développée par Ted Sider. (shrink)

ABSTRACT Drawing inspiration from Fred Dretske, L. S. Carrier, John A. Barker, and Robert Nozick, we develop a tracking analysis of knowing according to which a true belief constitutes knowledge if and only if it is based on reasons that are sensitive to the fact that makes it true, that is, reasons that wouldn’t obtain if the belief weren’t true. We show that our sensitivity analysis handles numerous Gettier-type cases and lottery problems, blocks pathways leading to skepticism, and validates the (...) epistemic closure thesis that correct inferences from known premises yield knowledge of the conclusions. We discuss the plausible views of Ted Warfield and Branden Fitelson regarding cases of knowledge acquired via inference from false premises, and we show how our sensitivity analysis can account for such cases. We present arguments designed to discredit putative counterexamples to sensitivity analyses recently proffered by Tristan Haze, John Williams and Neil Sinhababu, which involve true statements made by untrustworthy informants and strange clocks that sometimes display the correct time while running backwards. Finally, we show that in virtue of employing the paradox-free subjunctive conditionals codified by Relevance Logic theorists instead of the paradox-laden subjunctive conditionals codified by Robert Stalnaker and David Lewis. (shrink)

Contributors: Steven Barbone, Laurent Bove, Edwin Curley, Valérie Debuiche, Michael Della Rocca, Simon B. Duffy, Daniel Garber, Pascale Gillot, Céline Hervet, Jonathan Israel, Chantal Jaquet, Mogens Lærke, Jacqueline Lagrée, Martin Lin, Yitzhak Y. Melamed, Pierre-François Moreau, Steven Nadler, Knox Peden, Alison Peterman, Charles Ramond, Michael A. Rosenthal, Pascal Sévérac, Hasana Sharp, Jack Stetter, Ariel Suhamy, Lorenzo Vinciguerra.

Bas van Fraassen has argued that explanatory reasoning does not provide confirmation for explanatory hypotheses because explanatory reasoning increases information and increasing information does not provide confirmation. We compare this argument with a skeptical argument that one should never add any beliefs because adding beliefs increases information and increasing information does not provide confirmation. We discuss the similarities between these two arguments and identify several problems with van Fraassen’s argument.

Evidentialism is one of the most sensible claims of recent philosophy. Yet it is often joined with other theses about the structure of justification and the nature of experience that are dubious. In this paper, I argue that experience is not a basic source of evidence. I contend that for an experience to justify a belief, it must be independently plausible that the experience is reliable based on background information. The paper develops an account of plausibility and examines cases, including (...) differences in expertise, clairvoyance, and social perceptions, to illustrate how background knowledge is necessary for the justification of experiential beliefs. I consider challenges from Bergmann's distinction between learned and unlearned doxastic responses and Lyons's inferential reliabilism. I conclude that these challenges do not succeed; perceptual evidence requires a broader perspective that supports the reliability of the experiential evidence. (shrink)

Conscious mental states are states we are in some way aware of. I compare higher-order theories of consciousness, which explain consciousness by appeal to such higher-order awareness (HOA), and first-order theories, which do not, and I argue that higher-order theories have substantial explanatory advantages. The higher-order nature of our awareness of our conscious states suggests an analogy with the metacognition that figures in the regulation of psychological processes and behaviour. I argue that, although both consciousness and metacognition involve higher-order psychological (...) states, they have little more in common. One thing they do share is the possibility of misrepresentation; just as metacognitive processing can misrepresent one’s cognitive states and abilities, so the HOA in virtue of which one’s mental states are conscious can, and sometimes does, misdescribe those states. A striking difference between the two, however, has to do with utility for psychological processing. Metacognition has considerable benefit for psychological processing; in contrast, it is unlikely that there is much, if any, utility to mental states’ being conscious over and above the utility those states have when they are not conscious. (shrink)

This paper articulates a way to ground a relatively high prior probability for grand explanatory theories apart from an appeal to simplicity. I explore the possibility of enumerating the space of plausible grand theories of the universe by using the explanatory properties of possible views to limit the number of plausible theories. I motivate this alternative grounding by showing that Swinburne’s appeal to simplicity is problematic along several dimensions. I then argue that there are three plausible grand views—theism, atheism, and (...) axiarchism—which satisfy explanatory requirements for plausibility. Other possible views lack the explanatory virtue of these three theories. Consequently, this explanatory grounding provides a way of securing a nontrivial prior probability for theism, atheism, and axiarchism. An important upshot of my approach is that a modest amount of empirical evidence can bear significantly on the posterior probability of grand theories of the universe. (shrink)

From Kant’s point of view, the puzzle about judgments of taste is that they claim to normativity—in Kant’s terms, to intersubjective validity or communicability—but nevertheless have only a subjective basis or “determining ground (Bestimmungsgrund).” The task of §9 of the Critique of Judgment in particular is to delineate an account of aesthetic response that accommodates Kant’s solution to this puzzle. If the aesthetic pleasure “precedes” the judgment—in other words, if the judgment is about the pleasure—then the judgment of taste would (...) be merely private, like other judgments about things that cause us pleasure. So the judgment must precede the pleasure. But “nothing… can be universally communicated except cognition, and representation so far as it belongs to cognition. (V:217) Therefore, the determining ground of the judgment of taste must be “the mental state encountered in the relation of the mental powers of representation to each other insofar as they relate a given cognition to cognition in general.” (V:217) A bit later, he calls this state of mind a “feeling of the free play of the powers of representation in a given representation for a given representation for a cognition in general.” The appeal to ‘cognition in general’ can do what Kant needs it to do only if it conveys the normativity of cognition simpliciter but not its conceptual determinacy. I want to propose that we take ‘cognition in general’ to mean ‘integration into a unified system of empirical cognition.’ If I am successful, it will have the consequence that the basis for the normativity of taste— that is, the expectation that others ought to agree with our judgments-- is the same as the basis for the normativity of cognitive judgments. (shrink)

Prerequisite to memory is a past distinct from present. Because wave evolution is both continuous and time-reversible, the undisturbed quantum system lacks a distinct past and therefore the possibility of memory. With the quantum transition, a reversibly evolving superposition of values yields to an irreversible emergence of definite values in a distinct and transient moment of time. The succession of such moments generates an irretrievable past and thus the possibility of memory. Bohm’s notion of implicate and explicate order provides a (...) conceptual basis for memory as a general feature of nature akin to gravity and electromagnetism. I propose that natural memory is an outcome of the continuity of implicate time in the context of discontinuous explicate time. Among the ramifications of natural memory are that laws of nature can propagate through time much like habits and that personal memory does not require neural information storage. (shrink)

The coherence of independent reports provides a strong reason to believe that the reports are true. This plausible claim has come under attack from recent work in Bayesian epistemology. This work shows that, under certain probabilistic conditions, coherence cannot increase the probability of the target claim. These theorems are taken to demonstrate that epistemic coherentism is untenable. To date no one has investigated how these results bear on different conceptions of coherence. I investigate this situation using Thagard’s ECHO model of (...) explanatory coherence. Thagard’s ECHO model provides a natural representation of the evidential significance of multiple independent reports. (shrink)

In this paper I defend two closely related claims. The first claim, to which the first section of the paper is devoted, is that for Kant taste is a sort of cognition, that is, a form of awareness of reality for which questions of justification are appropriate. Nevertheless, In our appreciation of natural beauty we are aware of the suitability of appearances for inclusion in a rational system, albeit in a way that is subject to important limitations in comparison with (...) scientific cognition. In the second section of the paper, I will use this reading of Kant’s theory of taste to throw new light on Kant’s account of genius later in the “Critique of Aesthetic Judgment.”. (shrink)

Johann Georg Hamann's "Metakritik über den Purismum der Vernunft" begins with an allusion to Hume's endorsement of Berkeley's rejection of abstract ideas. On the basis of a close examination of the text of the Metakritik, I show that Hamann's overall point is that Kant cannot, or anyway does not, justify the relation of his own linguistic framework to natural language. Thus the Critique cannot meet its own standard for critical self-examination.

By deriving the Lorentz transformation from the absolute speed of light, Einstein demonstrated the relativistic variability of space and time, enabling him to explain length contraction and time dilation without recourse to a "luminiferous ether" or preferred frame of reference. He also showed that clocks synchronized at a distance via light signals are not synchronized in a frame of reference differing from that of the clocks. However, by mislabeling the relativity of synchrony the "relativity of simultaneity," Einstein implied that this (...) effect concerns an actual difference in times from one frame to another rather than merely a failure of clock synchronization across frames. As a theory of length contraction and time dilation on the basis of relative motion in the context of the absolute speed of light, special relativity is the definitive interpretation of the Lorentz transformation and the correct explanation of relativistic phenomena. The relativity of simultaneity, as I demonstrate, plays no role in this explanation but instead provides apparent justification for a view of time in which the present moment is frame-dependent. In contrast to its legitimate application, special relativity fails as a theory of time on the basis of the relativity of simultaneity. (shrink)

The quantum measurement problem resolves according to the twofold nature of time. Whereas the continuous evolution of the wave function reflects the fundamental nature of time as continuous presence, the collapse of the wave function indicates the subsidiary aspect of time as the projection of instantaneity from the ongoing present. Each instant irreversibly emerges from the reversible temporal continuum implicit in the smoothly propagating wave function. The basis of this emergence is periodic conflict between quantum systems, the definitive resolution of (...) which requires the momentary reduction of each system from the potentially infinite dimensions of configuration space to the three dimensions of classical space at an instant. (shrink)

Birch et. al. see their model as incompatible with higher-order-thought (HOT) theories of consciousness, on which a state is conscious if one is in some suitable way aware of that state. They see higher-order (HO) awareness as an “extra ingredient”. But since Birch et al go on to say that “[t]his is not the place for a detailed discussion of HOT theories,” they don’t address why they take HO awareness to be an extra ingredient or why HOT theorists are convinced (...) that it’s needed. In this commentary we argue that higher-order theories are a crucial for understanding consciousness. (shrink)

When you and I seriously argue over whether a man of seventy is old enough to count as an "old man", it seems that we are appealing neither to our own separate standards of oldness nor to a common standard that is already fixed in the language. Instead, it seems that both of us implicitly invoke an ideal, shared standard that has yet to be agreed upon: the place where we ought to draw the line. As with other normative standards, (...) it is hard to know whether such borderlines exist prior to our coming to agree on where they are. But epistemicists plausibly argue that they must exist whether we ever agree on them or not, as this provides the only logically acceptable response to the sorites paradox. This paper argues that such boundaries do typically exist as hypothetical ideals, but not as determinate features of the present actual world. There is in fact no general solution to the paradox, but attention to practice in resolving vague disagreements shows that its instances can be dealt with separately, as they arise, in many reasonable ways. (shrink)

Conclusion: The present results support adequate psychometric properties in terms of factorial validity, reliability, convergent validity, and measurement invariance for the PHQ-4 in young adults in Hong Kong. The PHQ-4 demonstrated a substantial mediating role in the relationship between meaning in life and SI in the distress group. These findings support clinical relevance for using the PHQ-4 as a brief and valid measure of psychological distress in the Chinese context.

An atom is characterized mathematically as an evolving superposition of possible values of properties and experimentally as an instantaneous phenomenon with a precise value of a measured property. Likewise, an organism is to itself a flux of experience and to an observer a tangible body in a distinct moment. Whereas the implicit atom is the stream of computation represented by the smoothly propagating wave function, the implicit organism is both the species from which the body individuates and the personal mind (...) its behavior explicates. As with the wave computation that underlies the atom, the substance of the implicit organism is not matter but information. And like projection from a superposition of potential values to a single outcome in a precise and fleeting moment, the organism actualizes only one of the many possible behaviors calculated in the ongoing presence we know as consciousness. (shrink)

The foundation of irreversible, probabilistic time -- the classical time of conscious observation -- is the reversible and deterministic time of the quantum wave function. The tendency in physics is to regard time in the abstract, a mere parameter devoid of inherent direction, implying that a concept of real time begins with irreversibility. In reality time has no need for irreversibility, and every invocation of time implies becoming or flow. Neither symmetry under time reversal, of which Newton was well aware, (...) nor the absence of an absolute parameter, as in relativity, negates temporal passage. Far from encapsulating time, irreversibility is a secondary property dependent on the emergence of distinct moments from the ceaseless presence charted by the wave function. (shrink)

Disagreement is common: even informed, intelligent, and generally reasonable people often come to different conclusions when confronted with what seems to be the same evidence. Can the competing conclusions be reasonable? If not, what can we reasonably think about the situation? This volume examines the epistemology of disagreement. Philosophical questions about disagreement arise in various areas, notably politics, ethics, aesthetics, and the philosophy of religion: but this will be the first book focusing on the general epistemic issues arising from informed (...) disagreement. Ten leading philosophers offer specially written essays which together will offer a starting-point for future work on this topic. (shrink)

The problem of biological memory led Russell to propose the existence of mnemic causation, a mechanism by which past experience influences current thought directly, that is, without the need for a material intermediary in the form of a neural "memory trace." Russell appears to have been inspired by German biologist Richard Semon's concept of mnemic homophony, which conveys memory to consciousness on the basis of similarity between current and past circumstances. Semon, however, in no way denied a role for stable (...) neural structures or "engrams" in the memory process. In contrast to Russell, contemporary biologist Rupert Sheldrake provides a viable theory of memory by remaining true to Semon's original idea and expanding it beyond personal memory to the collective memory of species, encompassing not only mental but developmental memory. (shrink)

Suppositions can be introduced in either the indicative or subjunctive mood. The introduction of either type of supposition initiates judgments that may be either qualitative, binary judgments about whether a given proposition is acceptable or quantitative, numerical ones about how acceptable it is. As such, accounts of qualitative/quantitative judgment under indicative/subjunctive supposition have been developed in the literature. We explore these four different types of theories by systematically explicating the relationships canonical representatives of each. Our representative qualitative accounts of indicative (...) and subjunctive supposition are based on the belief change operations provided by AGM revision and KM update respectively; our representative quantitative ones are offered by conditionalization and imaging. This choice is motivated by the familiar approach of understanding supposition as `provisional belief revision' wherein one temporarily treats the supposition as true and forms judgments by making appropriate changes to their other opinions. To compare the numerical judgments recommended by the quantitative theories with the binary ones recommended by the qualitative accounts, we rely on a suitably adapted version of the Lockean thesis. Ultimately, we establish a number of new results that we interpret as vindicating the often-repeated claim that conditionalization is a probabilistic version of revision, while imaging is a probabilistic version of update. (shrink)

Here is a puzzle about aesthetic education. In a variety of contexts, we commit significant time, energy, and resources to aesthetic education. We teach (and in many cases publicly subsidize) university courses and degrees that have aesthetic education as their primary aim; we also invest public resources into museums, including enrichment programs that are also designed to afford aesthetic education. It would seem that if our commitment to aesthetic education is rational, then aesthetic appreciation is something that can be done (...) better or worse. However, we also, in a variety of contexts (oddly enough, some of them being the same sorts of contexts that are designed to abet aesthetic education), act as if it is true that there is no disputing taste. We may try to persuade students to come around to particular judgments, but we do not penalize students for judging one way or another. The aim of this paper is to dissolve the apparent puzzle of aesthetic education by clarifying its aims and advancing a conception of it that deemphasizes the role of taste. I claim that, pace “the default view of aesthetic education” (as I shall call it), the primary purpose of aesthetic education is not to educate taste. It is, rather, to facilitate the development of certain perceptual-cognitive capacities so as to enhance aesthetic experience and improve aesthetic appreciation. Thus, I call the view of aesthetic education advanced here “a perceptual-cognitive model”. (shrink)

Why are we conscious? What does consciousness enable us to do that cannot be done by zombies in the dark? This paper argues that introspective consciousness probably co-evolved as a "spandrel" along with our more useful ability to represent the mental states of other people. The first part of the paper defines and motivates a conception of consciousness as a kind of "double vision" – the perception of how things seem to us as well as what they are – along (...) lines recently explored by Peter Carruthers. The second part explains the basic socioepistemic function of consciousness and suggests an evolutionary pathway to this cognitive capacity that begins with predators and prey. The third part discusses the relevance of these considerations to the traditional problem of other minds. (shrink)

This study focuses on the engagement of children and youth in their communities and the ways they are included in and excluded from community life. Using a content analysis of a small town United States newspaper over a one-year period, examples of engagement were identified and classified into 12 categories: programs, clubs and special events; fundraising and community ser- vice; business and community support; participation in community events; school events; athle- tic and other performances; employment; involvement in local planning and (...) decision making; serving as a community representative; visibility and recognition; criminal activity and accidents; and use of public space. Examples of community exclusion were identified as well. Young peo- ple were engaged primarily through activities that were adult-directed or supervised, or organi- zed through schools, churches, and youth clubs. There was little involvement in local planning, decision making, or activism. Some evidence existed of peer teaching, leadership, and self-initia- ted activities, as well as intentional efforts by adults to give youth a greater voice in community activities. Implications include several ethical issues regarding the role of young people in com- munity life, particularly young children, and the need for greater awareness on the part of com- munities of the contributions young people can make. (shrink)

Because an unmeasured quantum system consists of information — neither tangible existence nor its complete absence — no property can be assigned a definite value, only a range of likely values should it be measured. The instantaneous transition from information to matter upon measurement establishes a gradient between being and not-being. A quantum system enters a determinate state in a particular moment until this moment is past, at which point the system resumes its default state as an evolving superposition of (...) potential values of properties, neither strictly being nor not-being. Like a “self-organized” chemical system that derives energy from breaking down environmental gradients, a quantum system derives information from breaking down the ontological gradient. An organism is a body in the context of energy and a mind in the context of information. (shrink)

Though Einstein explained time dilation without recourse to a universal frame of reference, he erred by abolishing universal present moments. Relative simultaneity is insufficiently relativistic insofar as it depends on the absolute equality of reference frames in the measurement of the timing of events. Yet any given set of events privileges the frame in which the events take place. Relative to those events, the privileged frame yields the correct measurement of their timing while all other frames yield an incorrect measurement. (...) Instead of multiple frames occupying multiple times, one frame is correct and all others incorrect within a shared present moment. With the collapse of relative simultaneity, we may regard time as a succession of universal moments. Absolute simultaneity, in turn, explains why an accelerated inertial frame dilates in time rather than regressing to a prior moment relative to non-accelerated frames. In the context of flowing time, absolute simultaneity predicts time dilation while relative simultaneity predicts time regression. Einstein's explanation of time dilation is therefore incomplete. (shrink)

By eliminating the need for an absolute frame of reference or ether, Einstein resolved the problem of the constancy of light-speed in all inertial frames but created a new problem in our understanding of time. The resolution of this problem requires no experimentation but only a careful analysis of special relativity, in particular the relativity of simultaneity. This concept is insufficiently relativistic insofar as Einstein failed to recognize that any given set of events privileges the frame in which the events (...) occur; relative to those events, only the privileged frame yields the correct measurement. Instead of equally valid frames occupying different times, one frame is correct and all others incorrect within a shared present moment. I conclude that (1) time is a succession of universal moments and (2) in the context of flowing time, time dilation requires absolute simultaneity, whereas relative simultaneity predicts a nonexistent phenomenon here dubbed time regression. (shrink)

Alex Worsnip's recent book, Fitting Things Together: Coherence and the Demands of Structural Rationality, provides a sustained, wide-ranging defence of dualism.

Bradford Hill (1965) highlighted nine aspects of the complex evidential situation a medical researcher faces when determining whether a causal relation exists between a disease and various conditions associated with it. These aspects are widely cited in the literature on epidemiological inference as justifying an inference to a causal claim, but the epistemological basis of the Hill aspects is not understood. We offer an explanatory coherentist interpretation, explicated by Thagard's ECHO model of explanatory coherence. The ECHO model captures the complexity (...) of epidemiological inference and provides a tractable model for inferring disease causation. We apply this model to three cases: the inference of a causal connection between the Zika virus and birth defects, the classic inference that smoking causes cancer, and John Snow’s inference about the cause of cholera. (shrink)

AI-supported methods for identifying and combating disinformation are progressing in their development and application. However, these methods face a litany of epistemic and ethical challenges. These include (1) robustly defining disinformation, (2) reliably classifying data according to this definition, and (3) navigating ethical risks in the deployment of countermeasures, which involve a mixture of harms and benefits. This paper seeks to expose and offer preliminary analysis of these challenges.

Commentary on Walsh, E. 2020. Cognitive transformation, dementia, and the moral weight of advance directives. The American Journal of Bioethics. 20(8): 54–64.

Je cherche à explorer comment l'expérience de la temporalité est multiforme et fortement perturbée à l'époque de la pandémie Covid-19 et des politiques de confinement, générant une expérience d'hétérochronie, qui remet en question notre rapport à la vie.

The genetic modification of pigs as a source of transplantable organs is one of several possible solutions to the chronic organ shortage. This paper describes existing ethical tensions in xenotransplantation (XTx) that argue against pursuing it. Recommendations for lifelong infectious disease surveillance and notification of close contacts of recipients are in tension with the rights of human research subjects. Parental/guardian consent for pediatric xenograft recipients is in tension with a child’s right to an open future. Individual consent to transplant is (...) in tension with public health threats that include zoonotic diseases. XTx amplifies concerns about justice in organ transplantation and could exacerbate existing inequities. The prevention of infectious disease in source animals is in tension with the best practices of animal care and animal welfare, requiring isolation, ethologically inappropriate housing, and invasive reproductive procedures that would severely impact the well-being of intelligent social creatures like pigs. (shrink)

Fears of black-box algorithms are multiplying. Black-box algorithms are said to prevent accountability, make it harder to detect bias and so on. Some fears concern the epistemology of black-box algorithms in medicine and the ethical implications of that epistemology. Durán and Jongsma (2021) have recently sought to allay such fears. While some of their arguments are compelling, we still see reasons for fear.

It seems natural to choose whether to have a child by reflecting on what it would be like to actually have a child. I argue that this natural approach fails. If you choose to become a parent, and your choice is based on projections about what you think it would be like for you to have a child, your choice is not rational. If you choose to remain childless, and your choice is based upon projections about what you think it (...) would be like for you to have a child, your choice is not rational. This suggests we should reject our ordinary conception of how to make this life-changing decision, and raises general questions about how to rationally approach important life choices. (shrink)

The question I want to explore is whether experience supports an antireductionist ontology of time, that is, whether we should take it to support an ontology that includes a primitive, monadic property of nowness responsible for the special feel of events in the present, and a relation of passage that events instantiate in virtue of literally passing from the future, to the present, and then into the past.

When medical assistance in dying (MAiD) was legalized in Canada in June 2016, the question of allowing decisionally capable persons to make advance requests in anticipation of later incapacity was reserved for further consideration during the mandatory parliamentary review originally scheduled to begin in June 2020 (but since delayed by COVID-19). In its current form the legislation does not permit such requests, since it stipulates that at the time at which the procedure is to be administered the patient must give (...) “express consent” to receiving it. Since express consent presupposes decisional capacity, this requirement rules out administering MAiD to a patient who has lost capacity. Amendments to the legislation passed by Parliament in March 2021 open the door slightly by allowing advance requests by patients after they have been approved for MAiD, if they fear losing capacity before the procedure can be administered. But this provision would apply only to patients whose natural death was deemed to be “reasonably foreseeable”, and would continue to exclude (a) requests made after diagnosis of a “grievous and irremediable medical condition” but in advance of approval for MAiD, and (b) requests made before such a diagnosis. My aim in this paper is twofold: to explore the ethical and legal issues concerning advance requests for MAiD, and to argue for expanding provision for such requests to include both of these further scenarios. (shrink)

Galileo’s Error is a superlative work of public philosophy, particularly as a way of introducing modern academic panpsychism to a broader audience. In this commentary, I reflect on an issue that is prominent, though often with different background concerns, in both academic and popular discourse: what it means to be ‘scientific’ or ‘unscientific’. Panpsychism is not itself a scientific hypothesis, but neither is it (as critics sometimes claim) in conflict with science. Indeed, Goff argues, and I agree, that panpsychism is (...) an eminently scientific worldview, in the sense of a way of viewing reality that accords with and embraces what science reveals. But what exactly it means to ‘accord with and embrace’ science is disputed; this paper tries to untangle some of the threads. (shrink)

In this open peer commentary, we categorize the possible “neuroscience in national security” definitions of misuse of science and identify which, if any, are uniquely presented by advances in neuroscience. To define misuse, we first define what we would consider appropriate use: the application of reasonably safe and effective technology, based on valid and reliable scientific research, to serve a legitimate end. This definition presents distinct opportunities for assessing misuse: misuse is the application of invalid or unreliable science, or is (...) the use of reliable scientific methods to serve illegitimate ends. Ultimately, we conclude that while national security is often a politicized issue, assessing the state of scientific progress should not be. (shrink)

Le but de ce texte est de mettre en évidence les équi­valences entre la façon dont le concept de conatus résout, dans l'Éthique, le problème de l'unité modale complexe. en rendant consis­tant le concept de chose singulière en tant que celle-ci doit être consi­dérée comme un légitime sujet d'attribution d'états, et la façon dont ce même concept dessine le rapport cognitif de l'esprit avec lui-même, rapport par lequel l'esprit se saisit comme sujet de ses états et qui ca­ractérise la notion (...) moderne de subjectivité. Ainsi, en éclairant cet as­pect du concept spinoziste de chose singulière. on comprendra aussi, de façon indirecte, l'une des conditions par lesquelles les choses peuvent, dans la doctrine spinoziste, devenir des objets ou des signes pour la connaissance humaine. (shrink)

This year’s topic is “Genomics and Philosophy of Race.” Different researchers might work on distinct subsets of the six thematic clusters below, which are neither mutually exclusive nor collectively exhaustive: (1) Concepts of ‘Race’; (2) Mathematical Modeling of Human History and Population Structure; (3) Data and Technologies of Human Genomics; (4) Biological Reality of Race; (5) Racialized Selves in a Global Context; (6) Pragmatic Consequences of ‘Race Talk’ among Biologists.

I defend a one category ontology: an ontology that denies that we need more than one fundamental category to support the ontological structure of the world. Categorical fundamentality is understood in terms of the metaphysically prior, as that in which everything else in the world consists. One category ontologies are deeply appealing, because their ontological simplicity gives them an unmatched elegance and spareness. I’m a fan of a one category ontology that collapses the distinction between particular and property, replacing it (...) with a single fundamental category of intrinsic characters or qualities. We may describe the qualities as qualitative charactersor as modes, perhaps on the model of Aristotelian qualitative (nonsubstantial) kinds, and I will use the term “properties” interchangeably with “qualities”. The qualities are repeatable and reasonably sparse, although, as I discuss in section 2.6, there are empirical reasons that may suggest, depending on one’s preferred fundamental physical theory, that they include irreducibly intensive qualities. There are no uninstantiated qualities. I also assume that the fundamental qualitative natures are intrinsic, although physics may ultimately suggest that some of them are extrinsic. On my view, matter, concrete objects, abstract objects, and perhaps even spacetime are constructed from mereological fusions of qualities, so the world is simply a vast mixture of qualities, including polyadic properties (i.e., relations). This means that everything there is, including concrete objects like persons or stars, is a quality, a qualitative fusion, or a portion of the extended qualitative fusion that is the worldwhole. I call my view mereological bundle theory. (shrink)